These are more likely in people with naturally low blood pressure, since Minoxidil is a vasodilator (it relaxes blood vessels). Minoxidil doesn’t increase testosterone, reduce it, or significantly influence how it’s processed in the body. Other treatments, like Finasteride (Propecia), work by reducing the amount of DHT in the body. DHT is a by-product of testosterone, converted in the body by the enzyme 5-alpha-reductase. Studies suggest that around 60–70% of men see improvement in hair density with consistent use. This supports healthier follicle function and, in many cases, leads to visible regrowth. However, we are unaware of any reports in the medical literature describing the use and effectiveness of topical minoxidil to stimulate facial hair growth in trans males. Future research in trans males should look towards establishing the efficacy and safety of topical minoxidil (in its two main strengths and different preparations) using clinically meaningful endpoints for facial hair growth. Firstly, for transmasculine individuals on testosterone, facial hair growth may occur slowly and/or to an insufficient extent despite achieving target serum testosterone levels. While testosterone monotherapy can encourage facial hair growth, this case report suggests that minoxidil alone may also be effective in doing so and provides a new pharmacological option for TGD individuals assigned female at birth. Consistent with this, some transmasculine adults in online forums have described use of over-the-counter topical minoxidil to augment facial hair growth in the context of pre-existing systemic testosterone therapy. For instance, some individuals might want to delay or avoid testosterone, but desire access to treatments that help remove unwanted breast tissue (e.g. masculinizing chest surgery) or promote facial hair growth to avoid misgendering. Our doctors assure patients that these effects are rare, and many users experience no sexual side effects at all. However, it’s essential to note that these side effects were relatively uncommon, and the overall incidence remains very low. Despite these isolated cases, the consensus among specialists is that these side effects are uncommon. Although extremely rare, there have been reports of sexual side effects among Minoxidil users. Testosterone is a hormone produced primarily in the testicles in men and in smaller amounts in women’s ovaries. Previously, she held roles in the pharmaceutical sector (product management and chief medical officer) and served as a medical production editor for the journal Biomolecules and Biomedicine. She combines clinical work with research and medical editing, bringing a clear, evidence-based lens to patient education. Minoxidil can be a double-edged sword for hair regrowth. You can count on Scandinavian Biolabs to consistently deliver the trustworthy health information you deserve. When it comes to your health, you deserve information you can truly rely on - and earning your trust is our top priority. Gender affirming care for TGD youth includes social and psychological support and, in some cases, medical interventions. A total score of ≥8 is considered elevated for a Caucasian individual assigned female at birth. Modified Ferriman-Gallwey score evaluation before and after 3 months of minoxidil monotherapy. With his pediatrician’s agreement, he subsequently purchased minoxidil (5% lotion) and applied 1 mL twice daily to the beard area. No signs of male pattern baldness, acne or hirsutism (see Table 2 for modified Ferriman Gallwey score evaluation at baseline). However, due to legal requirements in Australia at the time, he was required to obtain Family Court approval to initiate therapy with testosterone.|Unexpectedly, despite no direct application to other areas, there was also an increase in pigmented body hair, suggestive of systemic absorption and effect. Women who use Minoxidil generally experience no hormonal disturbances. According to available studies, the effects of Minoxidil on fertility are minimal.}
